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DeCS
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Descriptor English:
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Integrin alpha6beta4
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Descriptor Spanish:
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Integrina alfa6beta4
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Descriptor Portuguese:
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Integrina alfa6beta4
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Synonyms English:
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A9 Antigen
Integrin alpha(6),beta(4)
Laminin-5 Receptor (alpha6beta4 Integrin)
TSP-180
Tumor Specific Protein-180 Complex
alpha(6)beta(4) Epithelial Integrin
alpha(6)beta(4) Integrin
alpha6 beta4 Integrin
Antigen, A9
Integrin, alpha6 beta4
Tumor Specific Protein 180 Complex
alpha6beta4, Integrin
beta4 Integrin, alpha6
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Tree Number:
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D12.776.543.750.705.408.460.170
D12.776.543.750.705.876.750
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Definition English:
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This intrgrin is a key component of HEMIDESMOSOMES and is required for their formation and maintenance in epithelial cells. Integrin alpha6beta4 is also found on thymocytes, fibroblasts, and Schwann cells, where it functions as a laminin receptor (RECEPTORS, LAMININ) and is involved in wound healing, cell migration, and tumor invasiveness. |
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History Note English:
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2003; use INTEGRIN ALPHA6BETA4 (NM) 1988-2002
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Allowable Qualifiers English:
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Record Number:
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37497
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Unique Identifier:
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D039161
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Occurrence in VHL:
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Similar:
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DeCS CID-10 LILACS
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